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| Name | | Position | | Team | | Cost | | IW | | TW1 | | TW2 | | CP |
| P Cech | | GK | | Chelsea | | 5.5m | | 5 | | 30 | | 0 | | 14 |
| R Carvalho | | DEF | | Chelsea | | 4.5m | | 4 | | 32 | | 0 | | 17 |
| P Konchesky | | DEF | | Fulham | | 2.0m | | 0 | | 34 | | 0 | | 7 |
| J Collins | | DEF | | West Ham United | | 1.5m | | 0 | | 43 | | 0 | | 11 |
| J O'Shea | | DEF | | Manchester United | | 4.0m | | 0 | | 25 | | 0 | | 4 |
| F Lampard | | MID | | Chelsea | | 8.5m | | 2 | | 58 | | 0 | | 40 |
| R Babel | | MID | | Liverpool | | 3.0m | | 0 | | 23 | | 0 | | 13 |
| R Giggs | | MID | | Manchester United | | 4.0m | | 0 | | 54 | | 0 | | 0 |
| D Drogba | | STR | | Chelsea | | 7.5m | | -1 | | 96 | | 0 | | 45 |
| M Owen | | STR | | Manchester United | | 3.0m | | 0 | | 19 | | 0 | | 16 |
| D Berbatov | | STR | | Manchester United | | 6.5m | | 0 | | 29 | | 0 | | 15 |
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| Transfer Window 1, In | | P Cech | | GK | | Chelsea | | 5.5m | | 5 | | 30 | | 0 | | 14 | | J Collins | | DEF | | West Ham United | | 1.5m | | 0 | | 43 | | 0 | | 11 | | R Giggs | | MID | | Manchester United | | 4.0m | | 0 | | 54 | | 0 | | 0 | |
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| Transfer Window 1, Out | | B Foster | | GK | | Manchester United | | 3.0m | | 0 | | 29 | | 0 | | 8 | | M Skrtel | | DEF | | Liverpool | | 4.5m | | -1 | | 7 | | 0 | | 3 | | K Richardson | | MID | | Sunderland | | 3.0m | | 0 | | -2 | | 0 | | 7 | |
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| Key | | IW = Points this week | | TW1 = Points up to first transfer window | | TW2 = Points between transfer windows 1 and 2 | | CP = Points since transfer window 2 | |
